Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
23549-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KGA/GAM/GAC Fusion Protein Ag20354 (1-140 aa encoded by BC038507)
偶联物
Unconjugated
形式
Liquid
浓度
0.49 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
GLS has 3 isoforms produced by alternative splicing and this antibody is specific to the 3 isoforms (KGA,GAM,GAC) of GLS.
Immunogen sequence: MMRLRGSGM LRDLLLRSPA GVSATLRRAQ PLVTLCRRPR GGGRPAAGPA AAARLHPWWG GGGWPAEPLA RGLSSSPSEI LQELGKGSTH PQPGVSPPAA PAAPGPKDGP GETDAFGNSE GKELVASGEN KIKQGLLPSL E (1-140 aa encoded by BC038507)
靶标信息
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GLS; glutaminase C; Glutaminase kidney isoform, mitochondrial; glutaminase, phosphate-activated; K-glutaminase; L-glutamine amidohydrolase
基因别名: 6330442B14; AAD20; AI314027; B230365M23Rik; GAC; GAM; GLS; GLS1; Glut; KGA; KIAA0838; RATGLUT
UniProt ID: (Human) O94925, (Mouse) D3Z7P3, (Rat) P13264
Entrez Gene ID: (Human) 2744, (Mouse) 14660, (Rat) 24398
