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产品信息
PA5-62252
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2643054
产品详细信息
Immunogen sequence: PQEAQKLAAE RARAPVVPYG VDLHYWGQEL PTAGKIVKSD SQHRFWKPSE VEEEVVNADI SEMLRSRHIT FAGKFEPVQH WCRAPRPDGR LCERQDRLK
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 81%.
靶标信息
The protein encoded by KIAA1530 appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in KIAA1530 can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants.
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生物信息学
蛋白别名: UV-stimulated scaffold protein A
基因别名: KIAA1530; UVSS3; UVSSA
UniProt ID: (Human) Q2YD98
Entrez Gene ID: (Human) 57654
