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Positive test controls include: HeLa, A-549, Mouse spleen, Mouse testis, Mouse heart, Mouse lung, Mouse brain, Rat spleen. The target is usually found in the following locations: Cytoplasm, Golgi apparatus, cytoskeleton, spindle.
Immunogen sequence: EICNEMVEQM QQREQWCSEH LDTQKELLEE MYEEKLNILK ESLTSFYQEE IQERDEKIEE LEALLQEARQ QSVAHQQSGS ELALRRSQRL AASASTQQLQ EVKAKLQQCK AELNSTTEEL HKYQKMLEPP PSAKPFTIDV DKKLEEGQKN IRLLRTELQK LGESLQSAER ACCHSTGAGK LRQALTTCDD ILIKQDQTLA ELQNNMVLVK LDLRKKAACI AEQYHTVLKL QGQVSAKKRL GTNQENQQPN QQPPGKKPFL RNLLPRTPTC QSSTDCSPYA RILRSRRSPL LKSGPFGKKY
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. [UniProt]
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GG10_2; Kinesin-like protein 174; Kinesin-like protein KIF20A; Mitotic kinesin-like protein 2; MKlp2; RAB6 interacting, kinesin-like (rabkinesin6); Rab6-interacting kinesin-like protein; Rabkinesin-6
基因别名: AA415432; KIF20A; MKLP2; RAB6KIFL
UniProt ID: (Human) O95235, (Mouse) P97329
Entrez Gene ID: (Human) 10112, (Mouse) 19348, (Rat) 361308
分子生物学功能:
microtubule binding motor protein