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KRT16 Antibody (CF808358) in IHC (P)
Immunohistochemical staining of paraffin-embedded human thyroid tissue within the normal limits using anti-KRT16 mouse monoclonal antibody.This figure shows negative staining. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA808358)(1:2000).
产品信息
CF808358
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI2F3
抗原
Full length human recombinant protein of human KRT16 produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CK-16; cytokeratin 16; Cytokeratin-16; focal non-epidermolytic palmoplantar keratoderma; K16; keratin 16, type I; Keratin, type I cytoskeletal 16; Keratin-16; type I keratin KA16
基因别名: CK16; FNEPPK; K16; K1CP; Ka16; KRT16; KRT16A; NEPPK; PC1
UniProt ID: (Human) P08779
Entrez Gene ID: (Human) 3868, (Rat) 303530
morphogenesis of an epithelium
inflammatory response
aging
biological_process
keratinocyte differentiation
negative regulation of cell migration
keratinization
hair cycle
innate immune response
intermediate filament cytoskeleton organization
keratinocyte migration
establishment of skin barrier
cytoskeleton organization
cell proliferation
epidermis development
