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Immunogen sequence: MEFYESAYFI VLIPSIVITV IFLFFWLFMK ETLYDEVLAK QKREQKLIPT KTDKKKAEKK KNKKKEIQNG NLHESDSESV PRDFKLSDAL AVEDDQVAPV; Positive Samples: A-549, A673, HeLa, MCF7; Cellular Location: Endoplasmic reticulum membrane, Single-pass type II membrane protein
Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CG-1 antigen; Kinectin; kinectin 1 (kinesin receptor); Kinesin receptor
基因别名: CG1; KIAA0004; KNT; KTN1; MU-RMS-40.19
UniProt ID: (Human) Q86UP2
Entrez Gene ID: (Human) 3895