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KappaB ras1 Antibody (MA1-41180) in WB
Western blot analysis of KappaB ras1 in human 293 cell lysate. Samples were incubated in KappaB ras1 monoclonal antibody (Product # MA1-41180 using a dilution of 0.5 µg/mL. Image using the Azide Free form of this antibody.
产品信息
MA1-41180
产品规格
种属反应
Bovine,
Dog,
Horse,
Human,
Mouse,
Non-human primate,
Pig,
Rat,
Xenopus
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
184C278
抗原
Synthetic peptide corresponding to residues 96-113 of human kB-Ras1.
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
PBS with 0.2% gelatin
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2056448
产品详细信息
Suggested positive control: 293 whole cell lysate.
靶标信息
KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with Ikappa-B (Ikappa-B), an inhibitor of the transcription factor NF-kappa-B. Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta, although Ikappa-B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive Ikappa-B-alpha-NF-kappa-B complexes can shuttle in and out of the nucleus, Ikappa-B-beta-NF-kappa-B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the Ikappa-B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of Ikappa-B-beta and regulating the rate of degradation of Ikappa-B-beta.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C15orf1; I-kappa-B-interacting Ras-like protein 1; I1PP2A; kappa B-ras 1; Kappa B-Ras protein 1; LANP; MAPM; MGC119787; MGC150373; NF-kappa-B inhibitor-interacting Ras-like protein 1; NFKB inhibitor interacting Ras-like 1; NFKB inhibitor interacting Ras-like protein 1; PHAP1; PHAPI; PP32
基因别名: 2400004O09Rik; kappaB-Ras1; KBRAS1; NKIRAS1; XELAEV_18033117mg
UniProt ID: (Human) Q9NYS0, (Mouse) Q8CEC5
Entrez Gene ID: (Bovine) 522875, (Pig) 100620195, (Human) 28512, (Horse) 100051752, (Dog) 477047, (Mouse) 69721, (Rat) 305751, (Xenopus) 100036787
