Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 86%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 92%
This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adenosine deaminase LACC1; Fatty acid metabolism-immunity nexus; Guanosine phosphorylase LACC1; Laccase domain-containing protein 1; Purine nucleoside phosphorylase LACC1; S-methyl-5'-thioadenosine phosphorylase LACC1
基因别名: 9030625A04Rik; Famin; Lacc1
UniProt ID: (Mouse) Q8BZT9
Entrez Gene ID: (Mouse) 210808