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产品信息
PA5-38033
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
18 amino acid peptide near the center of human LAMTOR2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2554637
产品详细信息
A recommended positive control is HepG2 cell lysate.
At least two isoforms of LAMTOR2 are known to exist; this antibody will detect both isoforms. LAMTOR2 antibody is not expected to cross-react with other LAMTOR family proteins.
靶标信息
The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family of proteins, and together with LAMTOR3 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling. This complex is involved in the regulation of late endosomal traffic and cellular proliferation and plays a role in cellular host defense against Salmonella infection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endosomal adaptor protein p14; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; late endosomal/lysosomal MP1 interacting protein; Late endosomal/lysosomal Mp1-interacting protein; MAPBP-interacting protein; MAPKSP1 adaptor protein; mitogen activated protein binding protein interacting protein; mitogen-activated protein binding protein interacting protein; Mitogen-activated protein-binding protein-interacting protein; mitogen-activated protein-binding protein-interacting protein (MAPBPIP); Ragulator complex protein LAMTOR2; roadblock domain containing 3; Roadblock domain-containing protein 3
基因别名: 2010111E04Rik; AL022628; ENDAP; HSPC003; LAMTOR2; MAPBPIP; MAPKSP1AP; P14; Rab25; Ragulator2; RGD1562501; ROBLD3
UniProt ID: (Human) Q9Y2Q5, (Mouse) Q9JHS3
Entrez Gene ID: (Human) 28956, (Mouse) 83409, (Rat) 295234
