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LILRB3 Antibody (MA5-24049) in WB, ICC/IF, IP
Nature communications 2023 -
Hepatic PirB is mainly expressed in monocyte-derived macrophages (MDMs). a PirB mRNA expression in different tissues ( n = 4). b , c Flow cytometry (FCM) and quantification of hepatic cells in the livers of the indicated mice ( n = 6 mice/group). d PirB mRNA expression in different hepatic cells ( n = 3). e Flow cytometry (FCM) of hepatic macrophages of the indicated groups. f Flow cytometry (FCM) of PirB ... View More
产品信息
MA5-24049
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
Mouse
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
326414
抗原
Mouse myeloma cell line NS0-derived recombinant mouse PIR-B Gly24-Gly635
偶联物
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2608224
产品详细信息
In Western blots, this antibody does not cross-react with recombinant mouse PIR-A.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
