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产品信息
PA5-87295
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human LILRB4.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2804042
产品详细信息
Purity is > 95% by SDS-PAGE.
靶标信息
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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生物信息学
蛋白别名: B4; CD85 antigen-like family member K; CD85k; glycoprotein 49 B; ILT-3; Immunoglobulin-like transcript 3; leucocyte Ig-like receptor B4; Leukocyte immunoglobulin-like receptor 5; Leukocyte immunoglobulin-like receptor subfamily B member 4; Leukocyte immunoglobulin-like receptor subfamily B member 4A; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4; LIR-5; Mast cell surface glycoprotein Gp49B; Monocyte inhibitory receptor HM18
基因别名: CD85K; gp49; Gp49b; HM18; ILT-3; ILT3; LILRB4; Lilrb4a; LIR-5; LIR5
UniProt ID: (Human) Q8NHJ6, (Mouse) Q64281
Entrez Gene ID: (Human) 11006, (Mouse) 14728
