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产品信息
19097-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LINGO1 Fusion Protein Ag13553 (36-351 aa encoded by BC011057)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SGSATGCPP RCECSAQDRA VLCHRKRFVA VPEGIPTETR LLDLGKNRIK TLNQDEFASF PHLEELELNE NIVSAVEPGA FNNLFNLRTL GLRSNRLKLI PLGVFTGLSN LTKLDISENK IVILLDYMFQ DLYNLKSLEV GDNDLVYISH RAFSGLNSLE QLTLEKCNLT SIPTEALSHL HGLIVLRLRH LNINAIRDYS FKRLYRLKVL EISHWPYLDT MTPNCLYGLN LTSLSITHCN LTAVPYLAVR HLVYLRFLNL SYNPISTIEG SMLHELLRLQ EIQLVGGQLA VVEPYAFRGL NYLRVLNVSG NQLTTLE (36-351 aa encoded by BC011057)
靶标信息
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: leucine rich repeat neuronal 6A; leucine-rich repeat; Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat neuronal 6A; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
基因别名: 4930471K13Rik; AV148400; LERN1; LINGO-1; LINGO1; LRRN6A; UNQ201; UNQ201/PRO227
UniProt ID: (Human) Q96FE5, (Mouse) Q9D1T0
Entrez Gene ID: (Human) 84894, (Rat) 315691, (Mouse) 235402
