Invitrogen

LIPG Polyclonal Antibody, HRP

产品信息

PA5-22914

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500

免疫组化（冰冻） (IHC (F))

Assay-Dependent

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A C-terminal synthetic peptide made to the human endothelial lipase protein sequence.

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偶联物

HRP HRP HRP

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

no preservative

保存条件

4° C, store in dark

运输条件

Wet ice

RRID

AB_11152164

产品详细信息

This antibody does not react with mouse endothelial lipase.

靶标信息

LIPG (Lipase G, Endohelial type) is an endothelial lipase which is a novel member of the lipoprotein lipase gene family. LIPG is synthesized by endothelial cells and functions at the site of synthesis. LIPG most likely plays a physiological role in modulating lipoprotein metabolism. Overexpressed LIPG has been shown to reduce HDL cholesterol levels, whereas an LIPG deficiency appears to be effective in elevating HDL cholesterol levels in animals. LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. Also, LIPG is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. LIPG is a carboxyl esterase that hydrolyzes high density lipoproteins, emulsifies triglycerides, is essential for the efficient digestion of dietary fats and can bind to heparin.

仅用于科研。不用于诊断过程。未经明确授权不得转售。