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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: linker of T-cell receptor pathways; Lymphocyte adapter protein; Lymphocyte-specific adapter protein Lnk; SH2B adapter protein 3; Signal transduction protein Lnk
基因别名: AI429800; IDDM20; LNK; SH2B3
UniProt ID: (Human) Q9UQQ2, (Mouse) O09039
Entrez Gene ID: (Human) 10019, (Mouse) 16923, (Rat) 58838