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产品信息
LOXL-101AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 570-607 on rat LOXL1 protein.
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
靶标信息
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
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生物信息学
蛋白别名: LOL; Lysyl oxidase 2; Lysyl oxidase homolog 1; Lysyl oxidase-like protein 1
基因别名: LOL; Lox2; LOXL; LOXL1
UniProt ID: (Human) Q08397, (Mouse) P97873
Entrez Gene ID: (Human) 4016, (Mouse) 16949, (Rat) 315714
