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LPAR3 (EDG7) (extracellular) Antibody (ALR-033-200UL) in WB
Western blot analysis of rat testis (lanes 1 and 3) and human OVCAR-3 (lanes 2 and 4): - 1,2. Anti-LPAR3 (EDG7) (extracellular) Antibody (#ALR-033), (1:200).3,4. Anti-LPAR3 (EDG7) (extracellular) Antibody , preincubated with LPAR3/EDG7 (extracellular) Blocking Peptide (#BLP-LR033).
产品信息
ALR-033-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)RSNTDTADEWTGTK, corresponding to amino acid residues 16-29 of rat LPA3receptor, Extracellular, N-terminus
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.EDG7 has been reported in human prostate, as well as rodent brain, kidney, lung, placenta, prostate, and testis. ESTs have been isolated from a normal prostate library, as well as cancer libraries of the head/neck, ovary, and thyroid.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium-mobilizing lysophosphatidic acid receptor LP-A3; endothelial cell differentiation gene 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; LPA receptor 3; LPA receptor EDG7; LPA-3; LPA3 Receptor; Lysophosphatidic acid receptor 3; Lysophosphatidic acid receptor Edg-7; putative G protein-coupled receptor snGPCR32; snGPCR32
基因别名: Edg-7; EDG7; GPCR; HOFNH30; LP-A3; LPA3; LPAR3; RP4-678I3
UniProt ID: (Human) Q9UBY5, (Mouse) Q9EQ31, (Rat) Q8K5E0
Entrez Gene ID: (Human) 23566, (Mouse) 65086, (Rat) 66025
activation of MAPK activity
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
positive regulation of cytosolic calcium ion concentration
chemical synaptic transmission
bleb assembly
positive regulation of collateral sprouting
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
positive regulation of calcium ion transport
signal transduction
G-protein coupled receptor signaling pathway
positive regulation of MAPK cascade
