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LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha lipase; Lipoprotein lipase; LPL; Phospholipase A1
基因别名: HDLCQ11; LIPD; LPL
UniProt ID: (Human) P06858
Entrez Gene ID: (Human) 4023