Product References
Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA.
Cells
Key J,Torres-Odio S,Bach NC,Gispert S,Koepf G,Reichlmeir M,West AP,Prokisch H,Freisinger P,Newman WG,Shalev S,Sieber SA,Wittig I,Auburger G
PA5-22034 was used in Western Blot to study global proteome profiles to define mitochondrial matrix peptidase ClpP substrates among the substrate-selecting AAA+ ATPase ClpX interactors.
Mon Nov 29 00:00:00 EST 2021
Identification of host proteins differentially associated with HIV-1 RNA splice variants.
eLife
Knoener R,Evans E,Becker JT,Scalf M,Benner B,Sherer NM,Smith LM
PA5-22034 was used in Western Blot, Immunocytochemistry to validate HyPR-MSSV for discovery of viral splice variant protein interactomes and provides an unprecedented resource of factors and pathways likely important to HIV-1 replication.
Thu Feb 25 00:00:00 EST 2021
Identification of host proteins differentially associated with HIV-1 RNA splice variants.
eLife
Knoener R,Evans E,Becker JT,Scalf M,Benner B,Sherer NM,Smith LM
PA5-22034 was used in Western Blot, Immunocytochemistry to validate HyPR-MSSV for discovery of viral splice variant protein interactomes and provides an unprecedented resource of factors and pathways likely important to HIV-1 replication.
Thu Feb 25 00:00:00 EST 2021
Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder.
JCI insight
Ruiz M,Cuillerier A,Daneault C,Deschênes S,Frayne IR,Bouchard B,Forest A,Legault JT,Vaz FM,Rioux JD,Burelle Y,Des Rosiers C
PA5-22034 was used in Western Blotting to show the value of lipidomics to unveil unexpected mechanisms underlying lipid dyshomeostasis ensuing from mitochondrial dysfunction, implying peroxisomes and liver which likely contribute to the pathophysiology of Leigh syndrome French-Canadian variant.
Thu Jul 25 00:00:00 EDT 2019
The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release.
The Journal of biological chemistry
Hedgepeth SC,Garcia MI,Wagner LE,Rodriguez AM,Chintapalli SV,Snyder RR,Hankins GD,Henderson BR,Brodie KM,Yule DI,van Rossum DB,Boehning D
PA5-22034 was used in immunoprecipitation to study the interaction between BRCA1 tumor suppressor and inositol 1,4,5-trisphosphate receptors and its effect on apoptotic calcium release
Fri Mar 13 00:00:00 EDT 2015