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产品信息
PA5-109269
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within Human APOER2 aa 494-722
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2854680
产品详细信息
Positive Control: Mouse placenat tissue, SH-SY-5Y, F9, HepG2, human placenta tissue.
靶标信息
Apolipoprotein E receptor 2 (ApoER2) is an NMDA associated protein found in neurons. It participates in important functions from guiding neurons in the embryonic brain to regulating synaptic signaling. It is also involved in debilitating neurodegenerative diseases such as schizophrenia and Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ApoE receptor 2; Apolipoprotein E receptor 2; low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; Low-density lipoprotein receptor-related protein 8; LRP-8
基因别名: APOER2; HSZ75190; LRP-8; LRP8; MCI1
UniProt ID: (Human) Q14114
Entrez Gene ID: (Human) 7804
negative regulation of transcription from RNA polymerase II promoter
retinoid metabolic process
proteolysis
lipid metabolic process
endocytosis
receptor-mediated endocytosis
signal transduction
cytokine-mediated signaling pathway
ammon gyrus development
cerebral cortex development
positive regulation of CREB transcription factor activity
reelin-mediated signaling pathway
response to drug
positive regulation of peptidyl-tyrosine phosphorylation
modulation of synaptic transmission
positive regulation of dendritic spine morphogenesis
positive regulation of protein tyrosine kinase activity
cellular response to growth factor stimulus
cellular response to cholesterol
positive regulation of dendrite development
