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Immunogen sequence: VEALTFSRE HGPGVAEPEV ATAPPEKEIP SLDQEKTKLE PGQPQLSPGI STIHLHPQFP VVIEKTSPPV PVEVAPEAST SSASQVIAPT QVTEINECTV NPDICGAGHC INLPVRYTCI CYEGYRFSEQ QRKCVDIDEC TQVQHLCSQG RCENTEGSFL CICPAGFMAS EEGTNCIDVD ECLRPDVCGE GHCVNTVGAF RCEYCDSGYR MTQRGRCEDI DECLNPSTCP DEQCVNSPGS YQCVPCTEGF RGWNGQCLDV DECLEPNVCA NGDCSNLEGS YMCSCHKGYT RTPDHKHCRD IDECQQGNLC VNGQCKNTEG SFRCTCGQGY QLSAAKDQCE DIDECQHRHL C (455-804 aa encoded by BC130289)
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins. The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Latent-transforming growth factor beta-binding protein 1; LTBP-1; MGC163161; TGF-beta1-BP-1; Transforming growth factor beta-1-binding protein 1
基因别名: LTBP1
UniProt ID: (Human) Q14766
Entrez Gene ID: (Human) 4052