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Product Details
PA5-99878
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human LTBP1(Accession Q14766), corresponding to amino acid residues S1674-E1721.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2818811
Product Specific Information
Antibody detects endogenous levels of total LTBP1.
Target Information
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins. The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LanC (bacterial lantibiotic synthetase component C)-like 1; latent TGF beta binding protein; Latent-transforming growth factor beta-binding protein 1; LTBP-1; MGC163161; TGF-beta-1-BP-1; TGF-beta1-BP-1; Transforming growth factor beta-1-binding protein 1; Transforming growth factor beta-1-masking protein large subunit; transforming growth factor-beta (TGF-beta) masking protein large subunit
Gene Aliases: 9430031G15Rik; 9830146M04; b2b1000Clo; Ltbp-1; LTBP1; Tgfb
UniProt ID: (Human) A1L3V1, (Mouse) Q8CG19, (Rat) Q00918
Entrez Gene ID: (Human) 4052, (Mouse) 268977, (Rat) 59107
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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