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产品信息
MA5-24650
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
CL3183
抗原
Recombinant protein corresponding to Human Laminin alpha-4
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2637265
产品详细信息
Immunogen sequence: ENLLNQAREL QAKAESSSDE AVADTSRRVG GALARKSALK TRLSDAVKQL QAAERGDAQQ RLGQSRLITE EANRTTMEVQ QATAPMANNL TNWSQNLQHF DSSAYNTAVN SARDAVRNLT EVVPQLLDQL RTVEQKRPAS
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.
Binds to an epitope located within the peptide sequence MANNLTNWSQNLQHF as determined by overlapping synthetic peptides.
靶标信息
Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: laminin [a]4; laminin alpha 4 chain; Laminin subunit alpha-4; laminin, alpha 4; Laminin-14 subunit alpha; Laminin-8 subunit alpha; Laminin-9 subunit alpha
基因别名: CMD1JJ; LAMA3; LAMA4; LAMA4*-1; RGD1560062
UniProt ID: (Human) Q16363, (Mouse) P97927
Entrez Gene ID: (Human) 3910, (Rat) 309816, (Mouse) 16775
