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NeoBiotechnologies
Langerin/CD207 (Marker of Langerhans Cells) Monoclonal Antibody (LGRN/7357)
产品信息
50489-MSM7-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
LGRN/7357
抗原
Recombinant fragment (around aa50-250) of human Langerin protein.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control:Human skin.
Cellular Location: Cell Surface. Cytoplasm.
靶标信息
Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; CD207; CD207 antigen, langerin; CD207 molecule, langerin; Langerhans cell specific c-type lectin; Langerin
基因别名: CD207; CLEC4K
UniProt ID: (Human) Q9UJ71
Entrez Gene ID: (Human) 50489
