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Recommended positive controls: HeLa, CD44-knockout HeLa, Raji, K562, THP-1.
Predicted reactivity: Mouse (94%), Rat (95%), Xenopus laevis (83%), Sheep (87%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ26625; Lck/Yes-related novel protein tyrosine kinase; lyn protein non-receptor kinase; p53Lyn; p56Lyn; Tyrosine-protein kinase Lyn; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
基因别名: AA407514; Hck-2; JTK8; LYN; p53Lyn; p56Lyn
UniProt ID: (Human) P07948, (Mouse) P25911, (Rat) Q07014
Entrez Gene ID: (Human) 4067, (Mouse) 17096, (Rat) 81515