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产品信息
PA5-64994
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2665086
产品详细信息
Immunogen sequence: SLLSHVEQLLR AFILKISVCD AVLDHNPPGC TFTVLVHTRE AATRNMEKIQ VIKDFPWILA DEQDVH
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
靶标信息
The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hREV7; MAD2 (mitotic arrest deficient, yeast, homolog)-like 2; MAD2-like protein 2; Mitotic arrest deficient 2-like protein 2; mitotic arrest deficient homolog-like 2; Mitotic spindle assembly checkpoint protein MAD2B; polymerase (DNA-directed), zeta 2, accessory subunit; REV7 homolog; RP3-330O12.4
基因别名: MAD2B; MAD2L2; POLZ2; REV7
UniProt ID: (Human) Q9UI95
Entrez Gene ID: (Human) 10459
negative regulation of transcription from RNA polymerase II promoter
regulation of cell growth
double-strand break repair
transcription, DNA-templated
actin filament organization
mitotic nuclear division
mitotic spindle assembly checkpoint
negative regulation of epithelial to mesenchymal transition
negative regulation of transcription by competitive promoter binding
positive regulation of peptidyl-serine phosphorylation
negative regulation of protein catabolic process
error-prone translesion synthesis
DNA damage response, signal transduction resulting in transcription
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of transcription, DNA-templated
cell division
negative regulation of canonical Wnt signaling pathway
negative regulation of ubiquitin protein ligase activity
negative regulation of cell-cell adhesion mediated by cadherin
negative regulation of transcription regulatory region DNA binding
