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Immunogen sequence: RRALSIKEQL QQEHRFLKRR LEQLSVQSVE RVRTDSTGSA VSTDDSEQEV DIEGMEFGPG ELDSVGSSSD ADDHYSLQSG TGGDSGFGPH CRRLGRPALS
This gene is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: max dimerization protein 4; max dimerizer 4; max-associated protein 4; max-interacting transcriptional repressor MAD4
基因别名: 2810410A03Rik; bHLHc12; Mad4
Entrez Gene ID: (Mouse) 17122