Invitrogen

MAPKAPK2 Recombinant Rabbit Monoclonal Antibody (4H8)

MAPKAPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MAPKAPK2 Antibody (MA5-38424) in IHC (P)

Immunohistochemistry (Paraffin) analysis of MAPKAPK2 in paraffin-embedded human breast cancer using MAPKAPK2 Monoclonal Antibody (Product # MA5-38424) diluted at 1:100. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primar... View More

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产品信息

MA5-38424

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:5,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

4H8

抗原

A synthesized peptide derived from human MAPKAP Kinase 2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.33 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol, 150mM NaCl

内含物

0.02% sodium azide

保存条件

-20°C or -80°C if preferred

运输条件

Wet ice

RRID

AB_2898338

产品详细信息

This antibody has been tested in direct-ELISA

靶标信息

MAPKAPK2 mediates p38 and ERK signaling in vivo. It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. MAPKAPK2 encodes a member of the Ser/Thr protein kinase family. MAPKAPK2 is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for MAPKAPK2.

仅用于科研。不用于诊断过程。未经明确授权不得转售。