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Recommended positive controls: mouse brain, rat brain.
Predicted reactivity: Mouse (98%), Rat (98%), Chimpanzee (89%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
EB3 is a 282 amino acid homologue of EB1, a protein known to bind APC (adenomatous polyposis coli). It has been shown to bind to tubulin in vitro and microtubules in vivo. Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle. EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: APC binding protein; EB1 protein family member 3; EB3; EBF3; End-binding protein 3; Microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
基因别名: AI790651; EB2; EB3; EBF3; EBF3-S; MAPRE3; RP3
UniProt ID: (Human) Q9UPY8, (Mouse) Q6PER3, (Rat) Q5XIT1
Entrez Gene ID: (Human) 22924, (Mouse) 100732, (Rat) 298848