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产品信息
PA5-56495
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2643766
产品详细信息
Immunogen sequence: PKKKKKFSFK KPFKLSGLSF KRNRKEGGGD SSASSPTEEE QEQGEIGACS DEGTAQEGKA AATPESQEPQ AKGAEASAAS EEEAGPQATE PSTPSG
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
靶标信息
MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332 amino acid protein that localizes to the plasma membrane and functions as a major cellular substrate for protein kinase C (PKC). MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195 amino acid protein that, like MARCKS, is a major substrate for PKC. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Mac-MARCKS; Macrophage myristoylated alanine-rich C kinase substrate; MARCKS-like 1; MARCKS-like protein 1; MARCKS-related protein
基因别名: F52; MACMARCKS; MARCKSL1; MLP; MLP1; MRP
UniProt ID: (Human) P49006
Entrez Gene ID: (Human) 65108
