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MARK2 Antibody (H00002011-D01P) in WB
Western Blot analysis of MARK2 expression in transfected 293T cell line (H00002011-T02) by MARK2 MaxPab polyclonal antibody.
Lane 1: MARK2 transfected lysate(84.30 KDa).
Lane 2: Non-transfected lysate.
Lane 1: MARK2 transfected lysate(84.30 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00002011-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MARK2 (NP_001034558.1, 1 a.a. approximately 755 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MIRGRNSATS ADEQPHIGNY RLLKTIGKGN FAKVKLARHI LTGKEVAVKI IDKTQLNSSS LQKLFREVRI MKVLNHPNIV KLFEVIETEK TLYLVMEYAS GGEVFDYLVA HGRMKEKEAR AKFRQIVSAV QYCHQKFIVH RDLKAENLLL DADMNIKIAD FGFSNEFTFG NKLDTFCGSP PYAAPELFQG KKYDGPEVDV WSLGVILYTL VSGSLPFDGQ NLKELRERVL RGKYRIPFYM STDCENLLKK FLILNPSKRG TLEQIMKDRW MNVGHEDDEL KPYVEPLPDY KDPRRTELMV SMGYTREEIQ DSLVGQRYNE VMATYLLLGY KSSELEGDTI TLKPRPSADL TNSSAPSPSH KVQRSVSANP KQRRFSDQAA GPAIPTSNSY SKKTQSNNAE NKRPEEDRES GRKASSTAKV PASPLPGLER KKTTPTPSTN SVLSTSTNRS RNSPLLERAS LGQASIQNGK DSLTMPGSRA STASASAAVS AARPRQHQKS MSASVHPNKA SGLPPTESNC EVPRPSTAPQ RVPVASPSAH NISSSGGAPD RTNFPRGVSS RSTFHAGQLR QVRDQQNLPY GVTPASPSGH SQGRRGASGS IFSKFTSKFV RRNLSFRFAR RNLNEPESKD RVETLRPHVV GSGGNDKEKE EFREAKPRSL RFTWSMKTTS SMEPNEMMRE IRKVLDANSC QSELHEKYML LCMHGTPGHE DFVQWEMEVC KLPRLSLNGV RFKRISGTSM AFKNIASKIA NELKL
靶标信息
MARK2 is a serine/threonine protein kinase involved in the control of cell polarity and microtubule stability. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. The human EMK1 was shown to be encoded by a single mRNA ubiquitously expressed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ELKL motif kinase; ELKL motif kinase 1; EMK-1; MAP/microtubule affinity-regulating kinase 2; MARK2; MGC99619; OTTHUMP00000218338; OTTHUMP00000218339; OTTHUMP00000218340; OTTHUMP00000218343; Par-1b; PAR1 homolog; PAR1 homolog b; Ser/Thr protein kinase PAR-1B; serine/threonine protein kinase EMK; Serine/threonine-protein kinase MARK2; testicular tissue protein Li 117
基因别名: EMK-1; EMK1; MARK2; PAR-1; Par-1b; Par1b
UniProt ID: (Human) Q7KZI7
Entrez Gene ID: (Human) 2011
microtubule cytoskeleton organization
mitophagy
neuron migration
protein phosphorylation
positive regulation of neuron projection development
Wnt signaling pathway
peptidyl-threonine phosphorylation
establishment of cell polarity
activation of protein kinase activity
intracellular signal transduction
establishment or maintenance of epithelial cell apical/basal polarity
protein autophosphorylation
regulation of axonogenesis
regulation of cytoskeleton organization
mitochondrion localization
cell-cell adhesion
