Invitrogen

MATN3 Polyclonal Antibody

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MATN3 Antibody (PA5-97958) in WB

Western Blot analysis of MATN3 using a MATN3 Polyclonal antibody (Product # PA5-97958) at a concentration of 4 µg/mL. Positive WB detected in: RAW264.7 whole cell lysate, SH-SY5Y whole cell lysate, HepG2 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 53 kDa.

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产品信息

PA5-97958

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:5,000

酶联免疫吸附实验 (ELISA)

Assay-Dependent

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human Matrilin-3 protein (1-240AA)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

3.54 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.03% ProClin 300

保存条件

-20°C or -80°C if preferred

运输条件

Wet ice

RRID

AB_2812572

靶标信息

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

仅用于科研。不用于诊断过程。未经明确授权不得转售。