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Invitrogen
MBL2 Monoclonal Antibody (3B6)
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产品信息
HYB 131-01-02
应用
建议稀释比
已发表文章
产品规格
已发表种属
Bovine
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3B6
抗原
Human MBL.
偶联物
形式
Liquid
浓度
1.04 mg/mL
保存条件
4°C, store in dark
运输条件
Wet ice
RRID
产品详细信息
HYB 131-01-02 is specific for MBL from human serum or plasma.
HYB 131-01-02 has been successfully used in ELISA, Western blotting and immunohistochemistry procedures. In Western blotting, HYB 131-01-02 reacts with human MBL both in its polymeric conformation and as a single subunit of molecular mass 26 kDa. Used as detection antibody in sandwich ELISA with a mannan or HYB 131-01-02 coat, HYB 131-01-02 is selective for normally oligomerized MBL. HYB 131-01-02 is also well suited for immunohistochemistry on human tissue samples, frozen or paraffin embedded, from liver and brain.
The HYB 131-01-02 immunogen is human MBL.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
靶标信息
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
