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This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MC3 receptor; MC3-R; Melanocortin receptor 3; obesity quantitative trait locus
基因别名: BMIQ9; MC3; MC3-R; MC3R; OB20; OQTL
UniProt ID: (Human) P41968, (Mouse) P33033, (Rat) P32244
Entrez Gene ID: (Human) 4159, (Mouse) 17201, (Rat) 29310