Invitrogen

MCD Polyclonal Antibody

产品信息

PA5-56803

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化 (IHC)

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human MCD. Recombinant protein control fragment (Product #RP-102339).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2643806

产品详细信息

Immunogen sequence: KEHGRNELFT DSECKEISEI TGGPINETLK LLLSSSEWVQ SEKLVRALQT PLMRLCAWYL YGEKHRGYAL NPVANFHLQN GAVLWRINWM ADVSLRGITG SCGLMANYRY FLEETGPNST SYLGSKIIKA SEQVLSLVAQ FQKNSKL

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.

靶标信息

MCD catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.

仅用于科研。不用于诊断过程。未经明确授权不得转售。