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Invitrogen

MCT1 Polyclonal Antibody

高级验证

1个已发表图片

3 篇参考文献

查看其他18个MCT1抗体

说明书

实验方案

技术支持

货号 PA5-72957

CNY 4,886.00

100 µg

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说明书

实验方案

技术支持

Application

MCT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MCT1 Antibody (PA5-72957) in IHC (P)

Immunohistochemical analysis of MCT1 in the submucosa of mouse intestine. Samples were incubated in MCT1 polyclonal antibody (Product # PA5-72957). Strong staining of lumen and crypt cells was observed with weaker cytoplasmic staining observed in the submucosa of mouse intestine.

MCT1 Antibody in Immunocytochemistry (ICC/IF)

Product Image Gallery

MCT1 Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across tissues owing to their inherent genetic constitution. The expression was observed across the tissues except in Mouse and Rat Brain using MCT1 Polyclonal Antibody (Product # PA5-72957) in Western Blot. {RE}

产品信息

PA5-72957

应用

建议稀释比

已发表文章

免疫印迹 (WB)

2-2.5 µg/ml

查看2篇已发表文章 2篇已发表文章

免疫组化（石蜡） (IHC (P))

1:200

免疫细胞化学 (ICC/IF)

1:100-1:250

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide made to an internal portion of the human Monocarboxylic acid transporter 1 protein (between residues 200-300) [UniProt P53985]

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偶联物

Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2718811

靶标信息

SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes. Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Knockdown of Astrocytic Monocarboxylate Transporter 4 in the Motor Cortex Leads to Loss of Dendritic Spines and a Deficit in Motor Learning.

Molecular neurobiology

Lundquist AJ,Llewellyn GN,Kishi SH,Jakowec NA,Cannon PM,Petzinger GM,Jakowec MW

PA5-72957 was used in Western Blotting to support a potential role for astrocyte-specific MCT4 and the ANLS in the neuroplasticity of the M1 primary motor cortex.

Tue Feb 01 00:00:00 UTC 2022

Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium.

Scientific data

Lee SH,Hadipour-Lakmehsari S,Kim DH,Di Paola M,Kuzmanov U,Shah S,Lee JJ,Kislinger T,Sharma P,Oudit GY,Gramolini AO

PA5-72957 was used in Western Blot, Immunocytochemistry to examine several proteomic- and RNA-Seq-based datasets of cardiac-enriched, cell-surface and membrane-associated proteins in human fetal and mouse neonatal ventricular cardiomyocytes.

Tue Dec 01 00:00:00 UTC 2020

Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium.

Scientific data

Lee SH,Hadipour-Lakmehsari S,Kim DH,Di Paola M,Kuzmanov U,Shah S,Lee JJ,Kislinger T,Sharma P,Oudit GY,Gramolini AO

Tue Dec 01 00:00:00 UTC 2020

Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium.

Scientific data

Lee SH,Hadipour-Lakmehsari S,Kim DH,Di Paola M,Kuzmanov U,Shah S,Lee JJ,Kislinger T,Sharma P,Oudit GY,Gramolini AO

Tue Dec 01 00:00:00 UTC 2020

Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium.

Scientific data

Lee SH,Hadipour-Lakmehsari S,Kim DH,Di Paola M,Kuzmanov U,Shah S,Lee JJ,Kislinger T,Sharma P,Oudit GY,Gramolini AO

Tue Dec 01 00:00:00 UTC 2020

生物信息学

蛋白别名: FLJ36745; MCT 1; MGC44475; monocarboxylate transporter; Monocarboxylate transporter 1; SLC16A1 protein; solute carrier 16 (monocarboxylic acid transporter), member 1; solute carrier family 16 (monocarboxylate transporter), member 1; solute carrier family 16 (monocarboxylic acid transporters), member 1; Solute carrier family 16 member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1)

基因别名: AL022710; HHF7; MCT; MCT1; MCT1D; RATMCT1; RNMCT1; SLC16A1

UniProt ID: (Human) P53985, (Rat) P53987, (Mouse) P53986

Entrez Gene ID: (Human) 6566, (Rat) 25027, (Mouse) 20501

功能

monocarboxylic acid transmembrane transporter activity lactate transmembrane transporter activity mevalonate transmembrane transporter activity symporter activity protein homodimerization activity organic cyclic compound binding protein binding secondary active monocarboxylate transmembrane transporter activity transporter

参与通路

pyruvate metabolic process lipid metabolic process monocarboxylic acid transport mevalonate transport response to food plasma membrane lactate transport glucose homeostasis regulation of insulin secretion leukocyte migration centrosome organization behavioral response to nutrient cellular response to organic cyclic compound lactate transmembrane transport transport transmembrane transport

MCT1 Polyclonal Antibody

MCT1 Antibody (PA5-72957) in IHC (P)

产品信息

PA5-72957

免疫印迹 (WB)

免疫组化（石蜡） (IHC (P))

免疫细胞化学 (ICC/IF)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

MCT1 Polyclonal Antibody

MCT1 Antibody (PA5-72957) in IHC (P)

产品信息

PA5-72957

免疫印迹 (WB)

免疫组化（石蜡） (IHC (P))

免疫细胞化学 (ICC/IF)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID .st0{fill-rule:evenodd;clip-rule:evenodd;fill:#A2A2A2;}

靶标信息

生物信息学

性能保障

随时为您服务

Your items have has been added!

RRID