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MDC Antibody (500-P176-1MG) in WB
Western Blot: To detect Murine MDC (CCL22) by Western Blot analysis MDC Polyclonal Antibody (Product # 500-P176-1MG) can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine MDC (CCL22) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
产品信息
500-P176-1MG
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived Recombinant Murine MDC (CCL22)
偶联物
形式
Lyophilized
浓度
0.1-1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
AB_2929649
产品详细信息
AA Sequence of recombinant protein: GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine MDC (CCL22). Anti-Murine MDC (CCL22)-specific antibody was purified by affinity chromatography employing an immobilized Murine MDC (CCL22) matrix.
Sandwich ELISA: To detect Murine MDC (CCL22) by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine MDC (CCL22) (500-P176Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine MDC (CCL22).
Western Blot: To detect Murine MDC (CCL22) by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine MDC (CCL22) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
靶标信息
CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Also, it is a chemotactic for monocytes. dendritic cells and natural killer cells. CCL22 is a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activated B and dendritic cell-derived; AW060611; C-C motif chemokine 22; CC chemokine ABCD-1; dendritic cell and B cell derived chemokine; MGC108943; MGC34554; RP24-69A20.1; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED); small inducible cytokine subfamily A, member 22; small inducible cytokine subfamily A22; Small-inducible cytokine A22
基因别名: ABCD-1; Abcd1; Ccl22; DCBCK; MDC; Scya22
UniProt ID: (Mouse) O88430
Entrez Gene ID: (Mouse) 20299
