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MDC1 Antibody (PA1-41131) in WB
Western blot was performed using Anti-MDC1 Polyclonal Antibody (Product # PA1-41131) and a 250kDakDa band corresponding to Mediator of DNA damage checkpoint protein 1 was observed across the cell lines tested. Nuclear enriched extracts (30 µg lysate) of HeLa (Lane 1), A-431 (Lane 2), HCT 116 (Lane 3), Mouse Testis (Lane 4) and Rat Testis (Lane 5) were electrophoresed using NuPAGE™ 3-8% Tris-Acetate Protein Gel (Product # EA0378BOX). Resolved proteins were then transferred onto a Nitrocellulose membrane (Product # IB23002) by iBlot® 2 Dry B... View More
产品信息
PA1-41131
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues 871-888 of human NFBD1.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
PBS with 0.2% gelatin
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2143136
产品详细信息
Suggested positive control: Jurkat whole cell lysate.
靶标信息
MDC1 participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DAAP-285E11.7; DKFZp781A0122; homologue to Drosophila photoreceptor protein calphotin; mediation of DNA damage checkpoint 1; Mediator of DNA damage checkpoint protein 1; mediator of DNA-damage checkpoint 1; MGC166888; Nuclear factor with BRCT domains 1
基因别名: 6820401C03; AA413496; KIAA0170; MDC1; mKIAA0170; NFBD1
UniProt ID: (Human) Q14676, (Mouse) Q5PSV9, (Rat) Q5U2M8
Entrez Gene ID: (Human) 9656, (Mouse) 240087, (Rat) 309595
