Product References
FAK inhibitor PF-562271 inhibits the migration and proliferation of high-grade serous ovarian cancer cells through FAK and FAK mediated cell cycle arrest.
Medical oncology (Northwood, London, England)
Pan Q,Wang Q,Zhao T,Zhao X,Liang Y,Shi M,Chen C,Lin F
Thu Jun 29 00:00:00 EDT 2023
EIF4A3-induced Circ_0001187 facilitates AML suppression through promoting ubiquitin-proteasomal degradation of METTL3 and decreasing m6A modification level mediated by miR-499a-5p/RNF113A pathway.
Biomarker research
Yang X,Han F,Hu X,Li G,Wu H,Can C,Wei Y,Liu J,Wang R,Jia W,Ji C,Ma D
Tue Jun 06 00:00:00 EDT 2023
A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR.
Molecular cancer
Song R,Ma S,Xu J,Ren X,Guo P,Liu H,Li P,Yin F,Liu M,Wang Q,Yu L,Liu J,Duan B,Rahman NA,Wołczyński S,Li G,Li X
Mon Jan 23 00:00:00 EST 2023
Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma.
Developmental cell
Gong Y,Zou S,Deng D,Wang L,Hu H,Qiu Z,Wei T,Yang P,Zhou J,Zhang Y,Zhu W,Xie X,Liao Z,Yang J,Zhang S,Liu A,Jiang Y,Zou Z,Bai X
Mon Feb 06 00:00:00 EST 2023
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM2.
Cell death discovery
Cai M,Xu S,Jin Y,Yu J,Dai S,Shi XJ,Guo R
Thu Jun 08 00:00:00 EDT 2023
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM2.
Cell death discovery
Cai M,Xu S,Jin Y,Yu J,Dai S,Shi XJ,Guo R
Thu Jun 08 00:00:00 EDT 2023
hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM2.
Cell death discovery
Cai M,Xu S,Jin Y,Yu J,Dai S,Shi XJ,Guo R
Thu Jun 08 00:00:00 EDT 2023
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Acta pharmaceutica Sinica. B
Feng Y,Han Y,Hu A,Qu Y,Hu Y,Wu H,Wang X,He L
Wed Feb 01 00:00:00 EST 2023
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Acta pharmaceutica Sinica. B
Feng Y,Han Y,Hu A,Qu Y,Hu Y,Wu H,Wang X,He L
Wed Feb 01 00:00:00 EST 2023
Flap endonuclease 1 Facilitated Hepatocellular Carcinoma Progression by Enhancing USP7/MDM2-mediated P53 Inactivation.
International journal of biological sciences
Bian S,Ni W,Zhu M,Zhang X,Qiang Y,Zhang J,Ni Z,Shen Y,Qiu S,Song Q,Xiao M,Zheng W
Fri Apr 15 00:00:00 EDT 2022
Flap endonuclease 1 Facilitated Hepatocellular Carcinoma Progression by Enhancing USP7/MDM2-mediated P53 Inactivation.
International journal of biological sciences
Bian S,Ni W,Zhu M,Zhang X,Qiang Y,Zhang J,Ni Z,Shen Y,Qiu S,Song Q,Xiao M,Zheng W
Fri Apr 15 00:00:00 EDT 2022
Flap endonuclease 1 Facilitated Hepatocellular Carcinoma Progression by Enhancing USP7/MDM2-mediated P53 Inactivation.
International journal of biological sciences
Bian S,Ni W,Zhu M,Zhang X,Qiang Y,Zhang J,Ni Z,Shen Y,Qiu S,Song Q,Xiao M,Zheng W
Fri Apr 15 00:00:00 EDT 2022
Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells.
Biochimica et biophysica acta. Molecular cell research
Bai Z,Zhou Y,Ye X,Li Y,Peng Y,Guan Q,Zhang W,Ma L
Tue Feb 01 00:00:00 EST 2022
A new FGF1 variant protects against adriamycin-induced cardiotoxicity via modulating p53 activity.
Redox biology
Xiao M,Tang Y,Wang J,Lu G,Niu J,Wang J,Li J,Liu Q,Wang Z,Huang Z,Guo Y,Gao T,Zhang X,Yue S,Gu J
Tue Feb 01 00:00:00 EST 2022
Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
Chemico-biological interactions
Tan J,Sun M,Yin J,Zhou Q,Zhao R,Chen Q,Sun H,Jiang C,Li S,He Y
Thu Dec 01 00:00:00 EST 2022
Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway.
Cell death discovery
Xu B,Wei Y,Liu F,Li L,Zhou S,Peng Y,Li B
Thu Aug 04 00:00:00 EDT 2022
Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway.
Cell death discovery
Xu B,Wei Y,Liu F,Li L,Zhou S,Peng Y,Li B
Thu Aug 04 00:00:00 EDT 2022
LncRNA MIAT enhances cerebral ischaemia/reperfusion injury in rat model via interacting with EGLN2 and reduces its ubiquitin-mediated degradation.
Journal of cellular and molecular medicine
Li S,Fu J,Wang Y,Hu C,Xu F
Mon Nov 01 00:00:00 EDT 2021
Ubiquitin-specific protease 7 mediates platelet-derived growth factor-induced pulmonary arterial smooth muscle cells proliferation.
Pulmonary circulation
Zhu Y,Zhang Q,Yan X,Liu L,Zhai C,Wang Q,Chai L,Li M
Sat Sep 25 00:00:00 EDT 2021
MeCP2 facilitates breast cancer growth via promoting ubiquitination-mediated P53 degradation by inhibiting RPL5/RPL11 transcription.
Oncogenesis
Tong D,Zhang J,Wang X,Li Q,Liu LY,Yang J,Guo B,Ni L,Zhao L,Huang C
Mon Jun 01 00:00:00 EDT 2020