Product References
Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo.
Cell death and differentiation
Phesse TJ,Myant KB,Cole AM,Ridgway RA,Pearson H,Muncan V,van den Brink GR,Vousden KH,Sears R,Vassilev LT,Clarke AR,Sansom OJ
MA1-23318 was used in immunohistochemistry to study apoptosis induced by p53 in response to DNA damage and the essential role of c-Myc
Sun Jun 01 00:00:00 EDT 2014
Salivary adenoid cystic carcinoma with an early phase of high-grade transformation: case report with an immunohistochemical analysis.
Diagnostic pathology
Kusafuka K,Miki T,Nakajima T
MA1-23318 was used in immunohistochemistry to report on a case of salivary adenoid cystic carcinoma with high-grade transformation
Tue Jul 02 00:00:00 EDT 2013
Identification of prognostic biomarkers for glioblastomas using protein expression profiling.
International journal of oncology
Jung Y,Joo KM,Seong DH,Choi YL,Kong DS,Kim Y,Kim MH,Jin J,Suh YL,Seol HJ,Shin CS,Lee JI,Kim JH,Song SY,Nam DH
MA1-23318 was used in immunohistochemistry - paraffin section to identify diagnostic and prognostic markers for glioblastoma
Sun Apr 01 00:00:00 EDT 2012
Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control.
Neoplasia (New York, N.Y.)
Li CH,Cheng YW,Liao PL,Kang JJ
MA1-23318 was used in western blot to study the role of p53 in apoptosis
Mon Feb 01 00:00:00 EST 2010
NOLC1, an enhancer of nasopharyngeal carcinoma progression, is essential for TP53 to regulate MDM2 expression.
The American journal of pathology
Hwang YC,Lu TY,Huang DY,Kuo YS,Kao CF,Yeh NH,Wu HC,Lin CT
MA1-23318 was used in western blot to investigate the influence of NOLC1 on the regulation of MDM2 expression by TP53
Wed Jul 01 00:00:00 EDT 2009
Epithelial expression of p53, mdm-2 and p21 in normal lip and actinic cheilitis.
Oral oncology
Martínez A,Brethauer U,Borlando J,Spencer ML,Rojas IG
MA1-23318 was used in immunohistochemistry to study changes in the expression of p53 pathway proteins during early lip carcinogenesis
Mon Sep 01 00:00:00 EDT 2008
Low-grade abdominopelvic sarcoma with myofibroblastic features (low-grade myofibroblastic sarcoma): clinicopathological, immunohistochemical, molecular genetic and ultrastructural study of two cases with literature review.
Journal of clinical pathology
Agaimy A,Wünsch PH,Schroeder J,Gaumann A,Dietmaier W,Hartmann A,Hofstaedter F,Mentzel T
MA1-23318 was used in immunohistochemistry to examine two cases of low-grade myofibroblastic sarcoma
Sat Mar 01 00:00:00 EST 2008
Potential role of apoptosis and apoptotic regulatory proteins in colorectal neoplasia: correlations with clinico-pathological parameters and survival.
Digestive diseases and sciences
Tzouvala M,Lazaris AC,Papatheodoridis GV,Kouvidou C,Papathomas TG,Kavantzas N,Elemenoglou I,Karamanolis DG,Agapitos E
MA1-23318 was used in immunohistochemistry to study the potential role of apoptosis and apoptotic regulatory proteins in colorectal neoplasia
Fri Feb 01 00:00:00 EST 2008
Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.
Molecular and cellular biology
Lindström MS,Jin A,Deisenroth C,White Wolf G,Zhang Y
MA1-23318 was used in immunocytochemistry to study the effect of cancer promoting missense mutations in the MSM2 zinc finger domain on its interaction with L5 and L11 and its ability to induce p53 degradation
Thu Feb 01 00:00:00 EST 2007
Cell cycle regulators show diagnostic and prognostic utility for differentiated thyroid cancer.
Annals of surgical oncology
Melck A,Masoudi H,Griffith OL,Rajput A,Wilkins G,Bugis S,Jones SJ,Wiseman SM
MA1-23318 was used in immunohistochemistry to study the diagnostic and prognostic value of cell cycle regulators in differentiated thyroid cancer
Sat Dec 01 00:00:00 EST 2007
p53 and mdm2 expression in colorectal carcinoma: a correlative analysis with clinical staging and histological parameters.
International journal of surgical pathology
Das P,Vaiphei K,Jain D,Wig JD
MA1-23318 was used in immunohistochemistry to investigate the expression and prognostic value of p53 and mdm2 in colorectal carcinoma
Mon Oct 01 00:00:00 EDT 2007
MDM2 protein expression is a negative prognostic marker in breast carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Turbin DA,Cheang MC,Bajdik CD,Gelmon KA,Yorida E,De Luca A,Nielsen TO,Huntsman DG,Gilks CB
MA1-23318 was used in immunohistochemistry to study the prognostic value of MDM2 protein expression in breast carcinoma
Sun Jan 01 00:00:00 EST 2006
Relationship between p53-associated proteins and estrogen receptor status in ovarian serous neoplasms.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Cho EY,Choi YL,Chae SW,Sohn JH,Ahn GH
MA1-23318 was used in immunohistochemistry - paraffin section to propose that the estrogen receptor regulates the p14ARF-MDM2-p53 pathway in ovarian serous neoplasms
Tue Feb 27 00:00:00 EST 2007
High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategies.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ricciardiello L,Ceccarelli C,Angiolini G,Pariali M,Chieco P,Paterini P,Biasco G,Martinelli GN,Roda E,Bazzoli F
MA1-23318 was used in immunohistochemistry to study the role of high thymidylate synthase expression in colorectal cancer with microsatellite instability
Wed Jun 01 00:00:00 EDT 2005
hTERT antagonizes p53-induced apoptosis independently of telomerase activity.
Oncogene
Rahman R,Latonen L,Wiman KG
MA1-23318 was used in western blot to study the role of hTERT in p53-mediated apoptosis
Thu Feb 17 00:00:00 EST 2005
Coupled induction of iNOS and p53 upregulation in renal resident cells may be linked with apoptotic activity in the pathogenesis of progressive IgA nephropathy.
Journal of the American Society of Nephrology : JASN
Qiu LQ,Sinniah R,Hsu SI
MA1-23318 was used in immunohistochemistry to study the involvement of nitric oxide synthase and p53 in the pathogenesis of progressive IgA nephropathy
Sun Aug 01 00:00:00 EDT 2004
Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants.
Journal of virology
Hann B,Balmain A
MA1-23318 was used in western blot to study the role of p53 mutants in restoring the replication of an E1B 55-kilodalton protein-deficient adenovirus
Sat Nov 01 00:00:00 EST 2003
Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway.
Molecular and cellular biology
Zhang Y,Wolf GW,Bhat K,Jin A,Allio T,Burkhart WA,Xiong Y
MA1-23318 was used in western blot to study the role of Ribosomal protein L11 and oncoprotein MDM2 in a p53-dependent ribosomal-stress checkpoint pathway
Mon Dec 01 00:00:00 EST 2003
Role of P53 and MDM2 in treatment response of human germ cell tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Kersemaekers AM,Mayer F,Molier M,van Weeren PC,Oosterhuis JW,Bokemeyer C,Looijenga LH
MA1-23318 was used in immunohistochemistry to study the role of p53 and MDM2 in the high sensitivity to chemotherapy of human germ cell tumors
Fri Mar 15 00:00:00 EST 2002
A melanoma-predisposing germline CDKN2A mutation with functional significance for both p16 and p14ARF.
Cancer letters
Hashemi J,Lindström MS,Asker C,Platz A,Hansson J,Wiman KG
MA1-23318 was used in immunocytochemistry to investigate the effect of melanoma-predisposing germline CDKN2A mutation on p16 and p14ARF activation
Fri Jun 28 00:00:00 EDT 2002
mdm2-p53 Interaction: lack of correlation with the response to 5-fluorouracil in advanced colorectal cancer.
Oncology
Paradiso A,Ranieri G,Simone G,Silvestris N,Costa A,De Lena M,Leone A,Vallejo C,Lacava J
MA1-23318 was used in immunohistochemistry to study the relationship between mdm2 and p53 expression and response to 5-fluorouracil treatment in advanced colorectal cancer
Fri Jul 19 00:00:00 EDT 2002
A unique basal pattern of p53 expression in ulcerative colitis is associated with mutation in the p53 gene.
Histopathology
Noffsinger AE,Belli JM,Miller MA,Fenoglio-Preiser CM
MA1-23318 was used in immunohistochemistry to investigate p53 immunoreactivity in ulcerative colitis
Thu Nov 01 00:00:00 EST 2001
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53.
Molecular cell
Zhang Y,Xiong Y
MA1-23318 was used in immunocytochemistry to study the effect of mutations in exon 2 of human ARF on its nucleolar localization and ability to regulate nuclear export of MDM2 and p53
Sat May 01 00:00:00 EDT 1999
Molecular aberrations of the G1-S checkpoint in myxoid and round cell liposarcoma.
The American journal of pathology
Dei Tos AP,Piccinin S,Doglioni C,Vukosavljevic T,Mentzel T,Boiocchi M,Fletcher CD
MA1-23318 was used in immunohistochemistry to study the molecular biology of the G1-S cell cycle checkpoint in myxoid and round cell liposarcoma
Mon Dec 01 00:00:00 EST 1997