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产品信息
91259
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
This antibody was raised against recombinant protein comprising amino acids 59-390 of mouse MEIS1.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
32mM sodium acetate/140mM HEPES, pH 7.5, with 30% glycerol, 70mM NaCl
内含物
0.035% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2793823
靶标信息
These gene encode homeobox proteins belonging to the TALE family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2; Homeobox protein Meis1; Homeobox protein Meis2; Homeobox protein Meis3; leukemogenic homolog protein; Meis homolog 2; Meis1, myeloid ecotropic viral integration site 1 homolog; Meis1, myeloid ecotropic viral integration site 1 homolog 2; Meis1, myeloid ecotropic viral integration site 1 homolog 3; Meis1-related gene 1; Meis1-related protein 1; Meis1-related protein 2; Meis2 homeobox; Myeloid ecotropic viral integration site 1; myeloid ecotropic viral integration site-related gene 1; TALE homeobox protein Meis2; WUGSC:H_NH0444B04.1
基因别名: A430109D20Rik; AI573393; C530044H18Rik; Evi8; HsT18361; MEIS1; MEIS2; MEIS3; MRG1; MRG2; Stra10
UniProt ID: (Human) O00470, (Human) O14770, (Human) Q9NPW2, (Mouse) Q60954, (Mouse) P97367, (Mouse) P97368
Entrez Gene ID: (Human) 4211, (Human) 4212, (Human) 56917, (Mouse) 17268, (Mouse) 17536, (Mouse) 17537
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein heterodimerization activity
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
transcription corepressor activity
transcription factor binding
sequence-specific DNA binding
DNA binding
homeodomain transcription factor
angiogenesis
lens morphogenesis in camera-type eye
transcription from RNA polymerase II promoter
locomotory behavior
megakaryocyte development
negative regulation of myeloid cell differentiation
negative regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
definitive hemopoiesis
negative regulation of transcription from RNA polymerase II promoter
eye development
visual learning
response to mechanical stimulus
pancreas development
response to growth factor
positive regulation of protein kinase B signaling
negative regulation of apoptotic signaling pathway
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
hemopoiesis
blood vessel morphogenesis
regulation of nucleic acid-templated transcription
