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OriGene

MEIS1 Monoclonal Antibody (OTI1B4), TrueMAB™

查看其他12个MEIS1抗体

说明书

实验方案

技术支持

货号 CF809622

此产品在中国无法购买

100 µg

说明书

实验方案

技术支持

抗体检测数据 (3)

Application

MEIS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MEIS1 Antibody (CF809622) in IHC (P)

Immunohistochemical staining of paraffin-embedded human bladder tissue within the normal limits using anti-MEIS1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA809622)(1:2000).

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产品信息

CF809622

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000

免疫组化（石蜡） (IHC (P))

1:2,000

流式细胞分析 (Flow)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

OTI1B4

抗原

Human recombinant protein fragment corresponding to amino acids 176-390 of human MEIS1 produced in E.coli.

查看免疫原

偶联物

Unconjugated

形式

Lyophilized

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 8% trehalose

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

靶标信息

Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE family of homeodomain-containing proteins.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Homeobox protein Meis1; leukemogenic homolog protein; Meis1, myeloid ecotropic viral integration site 1 homolog; MGC43380; WUGSC:H_NH0444B04.1

基因别名: MEIS1

UniProt ID: (Human) O00470

Entrez Gene ID: (Human) 4211

功能

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding protein heterodimerization activity homeodomain transcription factor

参与通路

angiogenesis lens morphogenesis in camera-type eye transcription from RNA polymerase II promoter locomotory behavior megakaryocyte development negative regulation of myeloid cell differentiation negative regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter definitive hemopoiesis