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Positive test controls include: BT-474, MCF7, U-251MG, M21. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.
Immunogen sequence: PLYNSFTELA QFRLSQDDVN GIQSLYGPPP ASTEEPLVPT KSVPSGSEMP AKCDPALSFD AISTLRGEYL FFKDRYFWRR SHWNPEPEFH LISAFWPSLP SYLDAAYEVN SRDTVFIFKG NEFWAIRGNE VQAGYPRGIH TLGFPPTIRK IDAAVSDKEK KKTYFFAADK YWRFDENSQS MEQGFPRLIA DDFPGVEPKV DAVLQAFGFF YFFSGSSQFE FDPNARMVTH ILKSNSWLHC
MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: matrix metallo protease; matrix metalloprotease 10; matrix metalloproteinase 10; matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase-10; MMP; MMP-10; MMPs; SL-2; stromelysin 2; Stromelysin-2; Transformation-associated protein 34A; transin 2; Transin-2
基因别名: AV377895; MMP-10; MMP10; SL-2; STMY2
UniProt ID: (Human) P09238, (Mouse) O55123, (Rat) P07152
Entrez Gene ID: (Human) 4319, (Mouse) 17384, (Rat) 117061