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Immunogen sequence: AALVWGPEKN KIYFFRGRDY WRFHPSTRRV DSPVPRRATD WRGVPSEIDA AFQDADGYAY FLRGRLYWKF DPVKVKALEG FPRLVGPDFF GCAEPANTFL
Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: matrix metallo protease; matrix metallopeptidase 11 (stromelysin 3); Matrix metalloproteinase 11 (stromelysin 3); Matrix metalloproteinase-11; MMP; MMP-11; MMPs; SL-3; stromelysin III; Stromelysin-3
基因别名: MMP-11; MMP11; SL-3; ST3; STMY3
UniProt ID: (Human) P24347, (Mouse) Q02853, (Rat) Q499S5
Entrez Gene ID: (Human) 4320, (Mouse) 17385, (Rat) 25481