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产品信息
23742-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MNT Fusion Protein Ag20666 (233-582 aa encoded by BC117563)
偶联物
Unconjugated
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RAHLKECFE TLKRNIPNVD DKKTSNLSVL RTALRYIQSL KRKEKEYEHE MERLAREKIA TQQRLAELKH ELSQWMDVLE IDRVLRQTGQ PEDDQASTST ASEGEDNIDE DMEEDRAGLG PPKLSHRPQP ELLKSTLPPP STTPAPLPPH PHPHPHSVAL PPAHLPVQQQ QPQQKTPLPA PPPPPAAPAQ TLVPAPAHLV ATAGGGSTVI AHTATTHASV IQTVNHVLQG PGGKHIAHIA PSAPSPAVQL APATPPIGHI TVHPATLNHV AHLGSQLPLY PQPVAVSHIA HTLSHQQVNG TAGLGPPATV MAKPAVGAQV VHHPQLVGQT VLNPVTMVTM PSFPVSTLKL A (233-582 aa encoded by BC117563)
靶标信息
The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHd3; Class D basic helix-loop-helix protein 3; MAX binding protein; Max-binding protein MNT; Max-interacting protein; MNT, MAX dimerization protein; Myc antagonist MNT; Protein ROX
基因别名: BHLHD3; MAD6; MNT; MXD6; ROX
UniProt ID: (Human) Q99583
Entrez Gene ID: (Human) 4335
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
transcription corepressor activity
protein dimerization activity
basic helix-loop-helix transcription factor
