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MPRIP/M-RIP Antibody (A304-823A) in IP
Detection of human MPRIP/M-RIP by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-MPRIP/M-RIP antibody (Product # A304-823A) (lot 1) used for IP at 6 µg per reaction. MPRIP/M-RIP was also immunoprecipitated by rabbit anti-MPRIP/M-RIP antibody A304-822A. For blotting immunoprecipitated MPRIP/M-RIP, A304-823A was used at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minu... View More
产品信息
A304-823A
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 975 to 1025 of human Myosin phosphatase Rho-interacting protein.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
靶标信息
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: M-RIP; Myosin phosphatase Rho-interacting protein; p116Rip; Rho interacting protein 3; Rho-interacting protein 3; RIP3
基因别名: KIAA0864; M-RIP; MPRIP; MRIP; p116Rip; RHOIP3; RIP3
UniProt ID: (Human) Q6WCQ1
Entrez Gene ID: (Human) 23164
