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Reconstitute in 100 µL of MQ water. Centrifuge to remove any insoluble material.
Specificity of this antibody: MRAP2.
Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MC2R accessory protein 2; Melanocortin-2 receptor accessory protein 2
基因别名: bA51G5.2; BMIQ18; C6orf117; MRAP2
UniProt ID: (Human) Q96G30
Entrez Gene ID: (Human) 112609