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Product Details
PA5-87125
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human MORF4L1.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2803875
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Esa1p-associated factor 3 homolog; MGC10631; MORF-related gene 15 protein; MORF-related gene on chromosome 15; Mortality factor 4-like protein 1; MRG15; Protein MSL3-1; testis expressed gene 189; Testis-expressed gene 189 protein; Transcription factor-like protein MRG15
Gene Aliases: Eaf3; FWP006; HSPC008; HSPC061; HsT17725; MEAF3; mKIAA4002; MORF4L1; MORFRG15; MRG15; PP368; S863-6; TEG-189; Tex189
UniProt ID: (Human) Q9UBU8, (Rat) Q6AYU1, (Mouse) P60762
Entrez Gene ID: (Human) 10933, (Rat) 300891, (Mouse) 21761
double-strand break repair via homologous recombination
chromatin remodeling
chromatin silencing
transcription, DNA-templated
cell proliferation
chromatin modification
histone deacetylation
regulation of growth
histone H4 acetylation
histone H2A acetylation
regulation of transcription, DNA-templated
DNA repair
DNA recombination
cellular response to DNA damage stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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