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Immunogen sequence: MTLEAIRYS RGSLQILDQL LLPKQSRYEA VGSVHQAWEA IRAMKVRGAP AIALVGCLSL AVELQAGAGG PGLAALVAFV RDKLSFLVTA RPTAVNMARA ARDLADVAAR EAEREGATEE AVRERVICCT EDMLEKDLRD NRSIGDLGAR HLLERVAPSG GKVTVLTHCN TGALATAGYG TALGVIRSLH SLGRLEHAFC TETRPYNQGA RLTAFELVYE QIPATLITDS MVAAAMAHRG VSAVVVGADR VVANGDTANK VGTYQLAIVA KHHGIPFYVA APSSSCDLRL ETGKEIIIEE RPGQELTDVN GVRIAAPGIG VWNPAFDVTP HDLITGGIIT ELGVFAPEEL RTALTTTISS RDGTLDGPQM (1-369 aa encoded by BC001703)
MGC3207 catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, MGC3207 promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: M1Pi; M1Pi {ECO:0000255|HAMAP-Rule:MF_03119}; Mediator of RhoA-dependent invasion; Methylthioribose-1-phosphate isomerase; methylthioribose-1-phosphate isomerase homolog; methylthioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}; MGC3207; MRI1; MTR-1-P isomerase; MTR-1-P isomerase {ECO:0000255|HAMAP-Rule:MF_03119}; S-methyl-5-thioribose-1-phosphate isomerase; S-methyl-5-thioribose-1-phosphate isomerase 1; S-methyl-5-thioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein; translation initiation factor eIF-2B subunit alpha/beta/delta-like protein {ECO:0000255|HAMAP-Rule:MF_03119}
基因别名: 2410018C20Rik; MRDI; MRI1; MTNA; RGD1307789; UNQ6390/PRO21135; Ypr118w
UniProt ID: (Human) Q9BV20, (Rat) Q5HZE4, (Mouse) Q9CQT1
Entrez Gene ID: (Human) 84245, (Rat) 288912, (Mouse) 67873