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MRP7 Antibody (PA5-75402) in WB
Western blot analysis of MRP7 in Lane 1: HEK293T whole cell lysate (40 µg), Lane 2: A549 whole cell lysate (40 µg), Lane 3: the Spleen tissue lysate of mouse (40 µg), Lane 4: SGC7901 whole cell lysate (40 µg), Lane 5: H9C2 whole cell lysate (40 µg). Samples were incubated with MRP7 polyclonal antibody (Product # PA5-75402) at a dilution of 1:500.
产品信息
PA5-75402
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 834-887 of Human MRP7.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719130
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ATP-binding cassette sub-family C member 10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; Multidrug resistance-associated protein 7
基因别名: ABCC10; EST182763; mFLJ00002; MRP7; SIMRP7
UniProt ID: (Human) Q5T3U5, (Mouse) Q8R4P9
Entrez Gene ID: (Human) 89845, (Rat) 316231, (Mouse) 224814
