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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39S ribosomal protein L18, mitochondrial; L18mt; Large ribosomal subunit protein uL18m
基因别名: HSPC071; L18mt; MRP-L18; MRPL18
UniProt ID: (Human) Q9H0U6
Entrez Gene ID: (Human) 29074