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Immunogen sequence: IKEVLLQAQD MAVRDHNVEF RSNLYIAEST SGRGQCLKRI RYHGRGRFGI MEKVYCHYFV KLVEGPPPPP EPPKTAVAHA KEYIQQLRSR TIVHTL
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39S ribosomal protein L22, mitochondrial; 39S ribosomal protein L25, mitochondrial; L22mt; L25mt; Large ribosomal subunit protein uL22m
基因别名: HSPC158; L22mt; MRP-L22; MRP-L25; MRPL22; MRPL25; RPML25
UniProt ID: (Human) Q9NWU5
Entrez Gene ID: (Human) 29093